Daniel Nachun

Affiliations

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA.
Department of Pathology, Stanford University, Stanford, CA, USA.

Publications (16)

Transcriptomic profiling of whole blood in 22q11.2 reciprocal copy number variants reveals that cell proportion highly impacts gene expression.

Brain, behavior, & immunity - health

Avec: Amy Lin , Jennifer K Forsyth , Gil D Hoftman , Leila Kushan-Wells , Maria Jalbrzikowski , Deepika Dokuru , Giovanni Coppola , Ania Fiksinski , Janneke Zinkstok , Jacob Vorstman , Daniel Nachun , Carrie E Bearden

Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease.

Nature communications

Avec: M D Mesbah Uddin , Ngoc Quynh H Nguyen , Bing Yu , Jennifer A Brody , Akhil Pampana , Tetsushi Nakao , Myriam Fornage , Jan Bressler , Nona Sotoodehnia , Joshua S Weinstock , Michael C Honigberg , Daniel Nachun , Romit Bhattacharya , Gabriel K Griffin , Varuna Chander , Richard A Gibbs , Jerome I Rotter , Chunyu Liu , Andrea A Baccarelli , Daniel I Chasman , Eric A Whitsel , Douglas P Kiel , Joanne M Murabito , Eric Boerwinkle , Benjamin L Ebert , Siddhartha Jaiswal , James S Floyd , Alexander G Bick , Christie M Ballantyne , Bruce M Psaty , Pradeep Natarajan , Karen N Conneely

Clonal hematopoiesis is associated with protection from Alzheimer's disease.

Nature medicine

Avec: Hind Bouzid , Julia A Belk , Max Jan , Yanyan Qi , Chloé Sarnowski , Sara Wirth , Lisa Ma , Matthew R Chrostek , Herra Ahmad , Daniel Nachun , Winnie Yao , Auteur inconnu , Alexa Beiser , Alexander G Bick , Joshua C Bis , Myriam Fornage , William T Longstreth , Oscar L Lopez , Pradeep Natarajan , Bruce M Psaty , Claudia L Satizabal , Joshua Weinstock , Eric B Larson , Paul K Crane , C Dirk Keene , Sudha Seshadri , Ansuman T Satpathy , Thomas J Montine , Siddhartha Jaiswal

Methylation differences in Alzheimer's disease neuropathologic change in the aged human brain.

Acta neuropathologica communications

Avec: Anna-Lena Lang , Tiffany Eulalio , Eddie Fox , Koya Yakabi , Syed A Bukhari , Claudia H Kawas , Maria M Corrada , Stephen B Montgomery , Frank L Heppner , David Capper , Daniel Nachun , Thomas J Montine

Transcriptomics and chromatin accessibility in multiple African population samples.

bioRxiv : the preprint server for biology

Avec: Marianne K DeGorter , Page C Goddard , Emre Karakoc , Soumya Kundu , Stephanie M Yan , Daniel Nachun , Nathan Abell , Matthew Aguirre , Tommy Carstensen , Ziwei Chen , Matthew Durrant , Vikranth R Dwaracherla , Karen Feng , Michael J Gloudemans , Naiomi Hunter , Mohana P S Moorthy , Cristina Pomilla , Kameron B Rodrigues , Courtney J Smith , Kevin S Smith , Rachel A Ungar , Brunilda Balliu , Jacques Fellay , Paul Flicek , Paul J McLaren , Brenna Henn , Rajiv C McCoy , Lauren Sugden , Anshul Kundaje , Manjinder S Sandhu , Deepti Gurdasani , Stephen B Montgomery

Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures.

The Journal of biological chemistry

Avec: Jiun-I Lai , Daniel Nachun , Lina Petrosyan , Benjamin Throesch , Erica Campau , Fuying Gao , Kristin K Baldwin , Giovanni Coppola , Joel M Gottesfeld , Elisabetta Soragni

GADD45A is a protective modifier of neurogenic skeletal muscle atrophy.

JCI insight

Avec: Jeffrey T Ehmsen , Riki Kawaguchi , Damlanur Kaval , Anna E Johnson , Daniel Nachun , Giovanni Coppola , Ahmet Höke

Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an east Asian cohort study.

European heart journal

Avec: Hyo-Jeong Ahn , Hong Yul An , Gangpyo Ryu , Jiwoo Lim , Choonghyun Sun , Han Song , Su-Yeon Choi , Heesun Lee , Taylor Maurer , Daniel Nachun , Soonil Kwon , So-Ryoung Lee , Gregory Y H Lip , Seil Oh , Siddhartha Jaiswal , Youngil Koh , Eue-Keun Choi

PRC2-AgeIndex as a universal biomarker of aging and rejuvenation.

Nature communications

Avec: Mahdi Moqri , Andrea Cipriano , Daniel J Simpson , Sajede Rasouli , Tara Murty , Tineke Anna de Jong , Daniel Nachun , Guilherme de Sena Brandine , Kejun Ying , Andrei Tarkhov , Karolina A Aberg , Edwin van den Oord , Wanding Zhou , Andrew Smith , Crystal Mackall , Vadim N Gladyshev , Steve Horvath , Michael P Snyder , Vittorio Sebastiano

Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders.

Biological psychiatry

Avec: Jennifer K Forsyth , Daniel Nachun , Michael J Gandal , Daniel H Geschwind , Ariana E Anderson , Giovanni Coppola , Carrie E Bearden

bioRxiv : the preprint server for biology

Avec: Tiffany Eulalio , Min Woo Sun , Olivier Gevaert , Michael D Greicius , Thomas J Montine , Daniel Nachun , Stephen B Montgomery

DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging.

Cellular and molecular gastroenterology and hepatology

Avec: Sophia K Lewis , Daniel Nachun , Martin G Martin , Steve Horvath , Giovanni Coppola , D Leanne Jones

Clonal hematopoiesis associated with epigenetic aging and clinical outcomes.

Aging cell

Avec: Daniel Nachun , Ake T Lu , Alexander G Bick , Pradeep Natarajan , Joshua Weinstock , Mindy D Szeto , Sekar Kathiresan , Goncalo Abecasis , Kent D Taylor , Xiuqing Guo , Russ Tracy , Peter Durda , Yongmei Liu , Craig Johnson , Stephen S Rich , David Van Den Berg , Cecilia Laurie , Tom Blackwell , George J Papanicolaou , Adolfo Correa , Laura M Raffield , Andrew D Johnson , Joanne Murabito , JoAnn E Manson , Pinkal Desai , Charles Kooperberg , Themistocles L Assimes , Daniel Levy , Jerome I Rotter , Alex P Reiner , Eric A Whitsel , James G Wilson , Steve Horvath , Siddhartha Jaiswal , Auteur inconnu

Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes.

Genome medicine

Avec: Michael J Gloudemans , Brunilda Balliu , Daniel Nachun , Theresia M Schnurr , Matthew G Durrant , Erik Ingelsson , Martin Wabitsch , Thomas Quertermous , Stephen B Montgomery , Joshua W Knowles , Ivan Carcamo-Orive

Organ aging signatures in the plasma proteome track health and disease.

Nature

Avec: Hamilton Se-Hwee Oh , Jarod Rutledge , Daniel Nachun , Róbert Pálovics , Olamide Abiose , Patricia Moran-Losada , Divya Channappa , Deniz Yagmur Urey , Kate Kim , Yun Ju Sung , Lihua Wang , Jigyasha Timsina , Dan Western , Menghan Liu , Pat Kohlfeld , John Budde , Edward N Wilson , Yann Guen , Taylor M Maurer , Michael Haney , Andrew C Yang , Zihuai He , Michael D Greicius , Katrin I Andreasson , Sanish Sathyan , Erica F Weiss , Sofiya Milman , Nir Barzilai , Carlos Cruchaga , Anthony D Wagner , Elizabeth Mormino , Benoit Lehallier , Victor W Henderson , Frank M Longo , Stephen B Montgomery , Tony Wyss-Coray

Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes.

Nature cardiovascular research

Avec: Philipp J Rauch , Jayakrishnan Gopakumar , Alexander J Silver , Daniel Nachun , Herra Ahmad , Marie McConkey , Tetsushi Nakao , Marc Bosse , Thiago Rentz , Nora Vivanco Gonzalez , Noah F Greenwald , Erin F McCaffrey , Zumana Khair , Manu Gopakumar , Kameron B Rodrigues , Amy E Lin , Eti Sinha , Maia Fefer , Drew N Cohen , Amélie Vromman , Eugenia Shvartz , Galina Sukhova , Sean Bendall , Michael Angelo , Peter Libby , Benjamin L Ebert , Siddhartha Jaiswal

Réseau de co-auteurs

Giovanni Coppola 5 collaborations

Siddhartha Jaiswal 5 collaborations

Stephen B Montgomery 5 collaborations

Alexander G Bick 3 collaborations

Pradeep Natarajan 3 collaborations

Thomas J Montine 3 collaborations

Steve Horvath 3 collaborations

Jennifer K Forsyth 2 collaborations

Carrie E Bearden 2 collaborations

Tetsushi Nakao 2 collaborations

Myriam Fornage 2 collaborations

Jerome I Rotter 2 collaborations

Eric A Whitsel 2 collaborations

Benjamin L Ebert 2 collaborations

Bruce M Psaty 2 collaborations

Herra Ahmad 2 collaborations

None None 2 collaborations

Joshua Weinstock 2 collaborations

Tiffany Eulalio 2 collaborations

Michael J Gloudemans 2 collaborations

Kameron B Rodrigues 2 collaborations

Brunilda Balliu 2 collaborations

Michael D Greicius 2 collaborations

Amy Lin 1 collaboration

Gil D Hoftman 1 collaboration

Leila Kushan-Wells 1 collaboration

Maria Jalbrzikowski 1 collaboration

Deepika Dokuru 1 collaboration

Ania Fiksinski 1 collaboration

Janneke Zinkstok 1 collaboration

Jacob Vorstman 1 collaboration

M D Mesbah Uddin 1 collaboration

Ngoc Quynh H Nguyen 1 collaboration

Bing Yu 1 collaboration

Jennifer A Brody 1 collaboration

Akhil Pampana 1 collaboration

Jan Bressler 1 collaboration

Nona Sotoodehnia 1 collaboration

Joshua S Weinstock 1 collaboration

Michael C Honigberg 1 collaboration

Romit Bhattacharya 1 collaboration

Gabriel K Griffin 1 collaboration

Varuna Chander 1 collaboration

Richard A Gibbs 1 collaboration

Chunyu Liu 1 collaboration

Andrea A Baccarelli 1 collaboration

Daniel I Chasman 1 collaboration

Douglas P Kiel 1 collaboration

Joanne M Murabito 1 collaboration

Eric Boerwinkle 1 collaboration

James S Floyd 1 collaboration

Christie M Ballantyne 1 collaboration

Karen N Conneely 1 collaboration

Hind Bouzid 1 collaboration

Julia A Belk 1 collaboration

Max Jan 1 collaboration

Yanyan Qi 1 collaboration

Chloé Sarnowski 1 collaboration

Sara Wirth 1 collaboration

Lisa Ma 1 collaboration

Matthew R Chrostek 1 collaboration

Winnie Yao 1 collaboration

Alexa Beiser 1 collaboration

Joshua C Bis 1 collaboration

William T Longstreth 1 collaboration

Oscar L Lopez 1 collaboration

Claudia L Satizabal 1 collaboration

Eric B Larson 1 collaboration

Paul K Crane 1 collaboration

C Dirk Keene 1 collaboration

Sudha Seshadri 1 collaboration

Ansuman T Satpathy 1 collaboration

Anna-Lena Lang 1 collaboration

Eddie Fox 1 collaboration

Koya Yakabi 1 collaboration

Syed A Bukhari 1 collaboration

Claudia H Kawas 1 collaboration

Maria M Corrada 1 collaboration

Frank L Heppner 1 collaboration

David Capper 1 collaboration

Marianne K DeGorter 1 collaboration

Page C Goddard 1 collaboration

Emre Karakoc 1 collaboration

Soumya Kundu 1 collaboration

Stephanie M Yan 1 collaboration

Nathan Abell 1 collaboration

Matthew Aguirre 1 collaboration

Tommy Carstensen 1 collaboration

Ziwei Chen 1 collaboration

Matthew Durrant 1 collaboration

Vikranth R Dwaracherla 1 collaboration

Karen Feng 1 collaboration

Naiomi Hunter 1 collaboration

Mohana P S Moorthy 1 collaboration

Cristina Pomilla 1 collaboration

Courtney J Smith 1 collaboration

Kevin S Smith 1 collaboration

Rachel A Ungar 1 collaboration

Jacques Fellay 1 collaboration

Paul Flicek 1 collaboration

Paul J McLaren 1 collaboration

Brenna Henn 1 collaboration

Rajiv C McCoy 1 collaboration

Lauren Sugden 1 collaboration

Anshul Kundaje 1 collaboration

Manjinder S Sandhu 1 collaboration

Deepti Gurdasani 1 collaboration

Jiun-I Lai 1 collaboration

Lina Petrosyan 1 collaboration

Benjamin Throesch 1 collaboration

Erica Campau 1 collaboration

Fuying Gao 1 collaboration

Kristin K Baldwin 1 collaboration

Joel M Gottesfeld 1 collaboration

Elisabetta Soragni 1 collaboration

Jeffrey T Ehmsen 1 collaboration

Riki Kawaguchi 1 collaboration

Damlanur Kaval 1 collaboration

Anna E Johnson 1 collaboration

Ahmet Höke 1 collaboration

Hyo-Jeong Ahn 1 collaboration

Hong Yul An 1 collaboration

Gangpyo Ryu 1 collaboration

Jiwoo Lim 1 collaboration

Choonghyun Sun 1 collaboration

Han Song 1 collaboration

Su-Yeon Choi 1 collaboration

Heesun Lee 1 collaboration

Taylor Maurer 1 collaboration

Soonil Kwon 1 collaboration

So-Ryoung Lee 1 collaboration

Gregory Y H Lip 1 collaboration

Seil Oh 1 collaboration

Youngil Koh 1 collaboration

Eue-Keun Choi 1 collaboration

Mahdi Moqri 1 collaboration

Andrea Cipriano 1 collaboration

Daniel J Simpson 1 collaboration

Sajede Rasouli 1 collaboration

Tara Murty 1 collaboration

Tineke Anna de Jong 1 collaboration

Guilherme de Sena Brandine 1 collaboration

Kejun Ying 1 collaboration

Andrei Tarkhov 1 collaboration

Karolina A Aberg 1 collaboration

Edwin van den Oord 1 collaboration

Wanding Zhou 1 collaboration

Andrew Smith 1 collaboration

Crystal Mackall 1 collaboration

Vadim N Gladyshev 1 collaboration

Michael P Snyder 1 collaboration

Vittorio Sebastiano 1 collaboration

Michael J Gandal 1 collaboration

Daniel H Geschwind 1 collaboration

Ariana E Anderson 1 collaboration

Min Woo Sun 1 collaboration

Olivier Gevaert 1 collaboration

Sophia K Lewis 1 collaboration

Martin G Martin 1 collaboration

D Leanne Jones 1 collaboration

Ake T Lu 1 collaboration

Mindy D Szeto 1 collaboration

Sekar Kathiresan 1 collaboration

Goncalo Abecasis 1 collaboration

Kent D Taylor 1 collaboration

Xiuqing Guo 1 collaboration

Russ Tracy 1 collaboration

Peter Durda 1 collaboration

Yongmei Liu 1 collaboration

Craig Johnson 1 collaboration

Stephen S Rich 1 collaboration

David Van Den Berg 1 collaboration

Cecilia Laurie 1 collaboration

Tom Blackwell 1 collaboration

George J Papanicolaou 1 collaboration

Adolfo Correa 1 collaboration

Laura M Raffield 1 collaboration

Andrew D Johnson 1 collaboration

Joanne Murabito 1 collaboration

JoAnn E Manson 1 collaboration

Pinkal Desai 1 collaboration

Charles Kooperberg 1 collaboration

Themistocles L Assimes 1 collaboration

Daniel Levy 1 collaboration

Alex P Reiner 1 collaboration

James G Wilson 1 collaboration

Theresia M Schnurr 1 collaboration

Matthew G Durrant 1 collaboration

Erik Ingelsson 1 collaboration

Martin Wabitsch 1 collaboration

Thomas Quertermous 1 collaboration

Joshua W Knowles 1 collaboration

Ivan Carcamo-Orive 1 collaboration

Hamilton Se-Hwee Oh 1 collaboration

Jarod Rutledge 1 collaboration

Róbert Pálovics 1 collaboration

Olamide Abiose 1 collaboration

Patricia Moran-Losada 1 collaboration

Divya Channappa 1 collaboration

Deniz Yagmur Urey 1 collaboration

Kate Kim 1 collaboration

Yun Ju Sung 1 collaboration

Lihua Wang 1 collaboration

Jigyasha Timsina 1 collaboration

Dan Western 1 collaboration

Menghan Liu 1 collaboration

Pat Kohlfeld 1 collaboration

John Budde 1 collaboration

Edward N Wilson 1 collaboration

Yann Guen 1 collaboration

Taylor M Maurer 1 collaboration

Michael Haney 1 collaboration

Andrew C Yang 1 collaboration

Zihuai He 1 collaboration

Katrin I Andreasson 1 collaboration

Sanish Sathyan 1 collaboration

Erica F Weiss 1 collaboration

Sofiya Milman 1 collaboration

Nir Barzilai 1 collaboration

Carlos Cruchaga 1 collaboration

Anthony D Wagner 1 collaboration

Elizabeth Mormino 1 collaboration

Benoit Lehallier 1 collaboration

Victor W Henderson 1 collaboration

Frank M Longo 1 collaboration

Tony Wyss-Coray 1 collaboration

Philipp J Rauch 1 collaboration

Jayakrishnan Gopakumar 1 collaboration

Alexander J Silver 1 collaboration

Marie McConkey 1 collaboration

Marc Bosse 1 collaboration

Thiago Rentz 1 collaboration

Nora Vivanco Gonzalez 1 collaboration

Noah F Greenwald 1 collaboration

Erin F McCaffrey 1 collaboration

Zumana Khair 1 collaboration

Manu Gopakumar 1 collaboration

Amy E Lin 1 collaboration

Eti Sinha 1 collaboration

Maia Fefer 1 collaboration

Drew N Cohen 1 collaboration

Amélie Vromman 1 collaboration

Eugenia Shvartz 1 collaboration

Galina Sukhova 1 collaboration

Sean Bendall 1 collaboration

Michael Angelo 1 collaboration

Peter Libby 1 collaboration